Zinedine Zidane will not start Karim Benzema, according to reports from MARCA and COPE. The French attacker isn't ready to play more than 45 minutes and Zidane will use him as a potential game changer off the bench if needed.
Therefore, Lucas Vazquez will make the starting lineup playing on the right wing. That will move Gareth Bale to the his natural left wing and Cristiano Ronaldo to the center of Madrid's offensive line in a role many fans and analysts want to see the Portuguese star take on more often.
Vazquez could be a very important player for Real Madrid as his work-rate will be needed against Atletico's intensity. He should be able to help Dani Carvajal against Yannick Ferreira Carrasco, one of Atletico's most dangerous weapons.
James Rodriguez or Marco Asensio could compete for a spot in the starting XI if Zidane decides not to start Vazquez.
Isco is expected to start the match in the midfield alongside Luka Modric and Mateo Kovacic.